Anum Azam Glasgow
​Postdoctoral scholar
UCSF profile
anum.azam (at) ucsf.edu

I am interested in self-assembling systems and protein complexes. I am working on developing methods to design and experimentally test chemically inducible dimerization systems to produce versatile protein biosensors and improve our understanding of protein-ligand interfaces.

UCSF IRACDA Postdoctoral Fellow
UCSF Chancellor's Postdoctoral Fellow
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Qualifications
  • Bachelor of Science, Biomedical Engineering, Johns Hopkins University
  • Ph.D., Bioengineering, UC Berkeley
Publications
  1. Glasgow AA*, Huang YM*, Mandell DJ*, Thompson M, Ritterson R, Loshbaugh AL, Pellegrino J, Krivacic C, Pache RA, Barlow KA, Ollikainen N, Jeon D, Kelly MJS, Fraser JS, Kortemme T. Computational design of a modular protein sense-response system. Science. 2019 Nov 22;366(6468):1024-1028. doi: 10.1126/science.aax8780. *co-first author
  2. Glasgow A, Tullman-Ercek D. Type III Secretion Filaments as Templates for Metallic Nanostructure Synthesis. Methods Mol Biol. 1798:155-171. 2018  doi:10.1007/978-1-4939-7893-9_12. 
  3. Glasgow AA, Wong HT, Tullman-Ercek D. A Secretion-Amplification Role for Salmonella enterica Translocon Protein SipD. ACS Synth Biol. 6(6):1006-1015. 2017. doi:10.1021/acssynbio.6b00335.
  4. Azam, A, Tullman-Ercek, D. Type-III secretion filaments as scaffolds for inorganic nanostructures. J R Soc Interface. (114):20150938. 2016. doi:10.1098/rsif.2015.0938
  5. Azam, A, Li, C, Metcalf, KJ, Tullman-Ercek, D. Type III secretion as a generalizable strategy for the production of full-length biopolymer-forming proteins. Biotechnol Bioeng. 2015. doi:10.1002/bit.25656
  6. Metcalf, KJ, Finnerty, C, Azam, A, Valdivia, E, Tullman-Ercek, D. Using transcriptional control to increase titers of secreted heterologous proteins by the type III secretion system. Appl Environ Microbiol. 2014. 80(19):5927-34. doi:10.1128/AEM.01330-14
  7. Azam, A, Laflin, KE, Jamal, M, Fernandes, R, Gracias, DH. Self-folding micropatterned polymeric containers. Biomed Microdevices. 2011. 13(1):51-8. doi:10.1007/s10544-010-9470-x
  8. Cho, JH, Azam, A, Gracias, DH. Three dimensional nanofabrication using surface forces. Langmuir. 2010. 26(21):16534-9. doi:10.1021/la1013889 
  9. Filipiak, DJ,* Azam, A,* Leong, TG, Gracias, DH. Hierarchical self-assembly of complex polyhedral microcontainers. J Micromech Microeng. 2009. 19(7):1-6. doi:10.1088/0960-1317/19/7/075012 *co-first author
  10. Azam, A, Leong, TG, Zarafshar, AM, Gracias DH. Compactness determines the success of cube and octahedron self-assembly. PLoS One. 2009. 4(2):e4451. doi:10.1371/journal.pone.0004451