Meytal Radzinski

I am interested in studying the allosteric control of protein interaction networks and the layers of regulation that determine interaction specificity of protein switches under different cellular and organismal conditions.

Rothschild Fellow

Education

• Bachelor of Science, Physics and Biology, Hebrew University of Jerusalem
• Master of Science, Structural Biochemistry and Molecular Biology, Hebrew University of Jerusalem
• Ph.D., Structural Biochemistry and Molecular Biology, Hebrew University of Jerusalem

Publications

1. Oppenheim, T.*, Radzinski, M.*, Braitbard, M., Brielle, E. S., Yogev, O., Goldberger, E., ... & Reichmann, D. (2023). The Cdc48 N-terminal domain has a molecular switch that mediates the Npl4-Ufd1-Cdc48 complex formation. Structure. https://doi.org/10.1016/j.str.2023.05.014
   
2. Grandy, C., Port, F., Radzinski, M., Singh, K., Erz, D., Pfeil, J., ... & Gottschalk, K. E. (2023). Remodeling of the focal adhesion complex by hydrogen-peroxide-induced senescence. Scientific Reports, 13(1), 9735 https://doi.org/10.1038/s41598-023-36347-2
   
3. Radzinski, M., Oppenheim, T., Metanis, N., Reichmann, D. (2021) The Cys Sense: Thiol Redox Switches Mediate Life Cycles of Cellular Proteins. Biomolecules, 11(3), 469. https://doi.org/10.3390/biom11030469
   
4. Reuter, W. H., Masuch, T., Ke, N., Lenon, M., Radzinski, M., ... , & Berkmen, M. (2019). Utilizing redox-sensitive GFP fusions to detect in vivo redox changes in a genetically engineered prokaryote. Redox biology, 26, 101280. https://doi.org/10.1016/j.redox.2019.101280
   
5. Bramasole, L., Sinha, A., Gurevich, S., Radzinski, M., Klein, Y., Panat, N., ... , & Pick, E. (2019). Proteasome lid bridges mitochondrial stress with Cdc53/Cullin1 NEDDylation status. Redox biology, 20, 533-543. https://doi.org/10.1016/j.redox.2018.11.010
   
6. Radzinski, M., & Reichmann, D. (2019). Variety is the spice of life: how to explore a redox-dependent heterogeneity in genomically identical cellular populations. Current Genetics, 65(1), 301-306.
   
7. Radzinski, M.*, Fassler, R.*, Yogev, O., Breuer, W., Shai, N., Gutin, J., ... , & Reichmann, D. (2018). Temporal profiling of redox-dependent heterogeneity in single cells. eLife, 7, e37623. https://doi.org/10.7554/eLife.37623
   

​