Lab members
Tanja Kortemme
My main scientific interests range from the details of the physical interactions between atoms and molecules to the architecture and evolution of interaction networks in complex biological systems. Education
Postdoctoral work Computational and structural biology at EMBL Heidelberg and the Howard Hughes Medical Institute, University of Washington, Seattle. Tanja's publications |
Postdoctoral scholars
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Simon Kretschmer
I am interested in developing protein-based biosensors for synthetic biology applications. In particular, I aim to design and experimentally characterize synthetic proteins that can sense and respond to small molecules of biomedical relevance. PBBR Postdoctoral Independent Research Grant Li Foundation Fellow Education
Simon's publications |
Lu Hong
I'm interested in designing biomolecular systems that function out of equilibrium. Specifically, my goal is to accelerate the period of the Kai oscillator, a post-translational circadian clock found in cyanobacteria. Education
Lu's publications |
Stephanie Crilly
I am interested in designing signaling proteins and systems, as well as developing tools to study endogenous signaling events. Education
Stephanie's publications |
Giuseppe Cimicata
I’m interested in designing a reversible switching system triggered by protein-protein interactions. In parallel, I’m working on the reengineering and minimization of Cas9. Education
Giuseppe's publications |
Yilun Qi
I am fascinated by the relationship between protein structure and function. I hope to leverage protein design technologies to sample a variety of protein structures and functions. Education
Yilun's publications |
graduate students
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Amy Guo
I am interested in the designability of dynamic proteins and mini-proteins. Currently, I am working on creating mini-ACE2 designs to bind the SARS-CoV-2 spike protein. NSF GRFP Fellow UCSF Discovery Fellow Education
Amy's publications |
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Connor Galvin
I am currently working on leveraging biological data to improve accuracy and efficiency in the computational design of de novo small molecule binding sites. Education
Connors's publications |
Dominic Grisingher
Protein switch design for protein-protein interactions. ARCS Foundation Fellow Education
Dom's publications |
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Ben Orr
co-mentored by Mike Keiser Protein design with deep learning. NSF GRFP Fellow Dr. Herbert Landahl Mathematical Biophysics Student Excellence Award Mary Anne Koda-Kimble Seed Award for Innovation Education
Ben's publications |
Deniz Akpinaroglu
Design of small-molecule binding proteins with deep learning. NSF GRFP Fellow Education
Deniz's publications |
Philipp Huettemann
Designing de novo signaling systems. Education
Philipp's publications |
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Catherine Kuhn
Designing de novo switches with deep learning. Education
Catherine's publications |
Radhika Dalal
I am using de novo design to control protein-DNA interactions. Education
Radhika's publications |
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Jon Zhang
co-mentored by Margaux Pinney I am leveraging approaches in high throughput biochemistry and machine learning to develop models of allosteric coupling in molecular switches. Education
Jon's publications |
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