Stephanie Crilly
Postdoctoral Scholar

I am interested in designing signaling proteins and systems, as well as developing tools to study endogenous signaling events.

Education​​

• Bachelor of Science, Microbiology, Penn State University
• PhD, Cellular & Molecular Biology, University of Michigan

Publications

1. Crilly SE, Ko W, Weinberg ZY, Puthenveedu MA. Conformational specificity of opioid receptors is determined by subcellular location irrespective of agonist. Elife. 2021 May 20;10:e67478. doi: 10.7554/eLife.67478.
   
2. Crilly SE, Puthenveedu MA. Compartmentalized GPCR Signaling from Intracellular Membranes. J Membr Biol. 2021 Jun;254(3):259-271. doi: 10.1007/s00232-020-00158-7.
   
3. Marti-Solano M, Crilly SE, Malinverni D, Munk C, Harris M, Pearce A, Quon T, Mackenzie AE, Wang X, Peng J, Tobin AB, Ladds G, Milligan G, Gloriam DE, Puthenveedu MA, Babu MM. Combinatorial expression of GPCR isoforms affects signalling and drug responses. Nature. 2020 Nov;587(7835):650-656. doi: 10.1038/s41586-020-2888-2.
   
4. Weinberg ZY, Crilly SE, Puthenveedu MA. Spatial encoding of GPCR signaling in the nervous system. Curr Opin Cell Biol. 2019 Apr;57:83-89. doi: 10.1016/j.ceb.2018.12.006.
   
5. Shiwarski DJ*, Crilly SE*, Dates A, Puthenveedu MA. Dual RXR motifs regulate nerve growth factor-mediated intracellular retention of the delta opioid receptor. Mol Biol Cell. 2019 Mar 1;30(5):680-690. doi: 10.1091/mbc.E18-05-0292. *co-first author
   
6. Corbit VL, Whalen TC, Zitelli KT, Crilly SY, Rubin JE, Gittis AH. Pallidostriatal Projections Promote β Oscillations in a Dopamine-Depleted Biophysical Network Model. J Neurosci. 2016 May 18;36(20):5556-71. doi: 10.1523/JNEUROSCI.0339-16.2016.
   
7. Khanna MR, Mattie FJ, Browder KC, Radyk MD, Crilly SE, Bakerink KJ, Harper SL, Speicher DW, Thomas GH. Spectrin tetramer formation is not required for viable development in Drosophila. J Biol Chem. 2015 Jan 9;290(2):706-15. doi: 10.1074/jbc.M114.615427.